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JPYZXZ reduced MDSC-related immunosuppressive cytokines in TME. (A–C) JPYZXZ diminished the expression levels of iNOS and Arg-1. (D–H) The expression levels of IL-10, IFN-γ, IL-6, TGF-β, and TNF-α in mice serum were measured using ELISA. Data are expressed as the mean ± SEM, n = 5 mice or n = 3 independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001.
