Table 1.
Baseline characteristics of included patients grouped by TGI level in patients younger than 65 years old.
| Variables | T1 (5.91–8.50) | T2 (8.50–9.04) | T3 (9.04–12.90) | p-value |
|---|---|---|---|---|
| N | 549 | 617 | 677 | – |
| Age, years, mean (SD) | 49.36 ± 11.16 | 51.99 ± 9.36 | 52.78 ± 8.19 | <0.001 |
| Male, n (%) | 362 (65.94) | 423 (68.56) | 467 (68.98) | 0.470 |
| Baseline NIHSS score, median (Q1–Q3) | 4 (1–8) | 4 (2–9) | 4 (2–8) | 0.270 |
| Time from onset to admission, hour, median (Q1–Q3) | 48 (24–120) | 72 (24–120) | 72 (24–120) | 0.974 |
| Hypertension, n (%) | 205 (37.34) | 316 (51.22) | 431 (63.66) | <0.001 |
| Diabetes, n (%) | 31 (5.65) | 91 (14.75) | 299 (44.17) | <0.001 |
| Atrial fibrillation, n (%) | 60 (10.93) | 55 (8.91) | 31 (4.58) | <0.001 |
| Rheumatic heart disease, n (%) | 59 (10.75) | 51 (8.27) | 27 (3.99) | <0.001 |
| Coronary heart disease, n (%) | 18 (3.28) | 12 (1.94) | 23 (3.40) | 0.213 |
| History of stroke, n (%) | 52 (9.47) | 58 (9.40) | 67 (9.90) | 0.887 |
| Drinking, n (%) | 156 (28.42) | 218 (35.33) | 241 (35.60) | 0.010 |
| Smoking, n (%) | 217 (39.53) | 307 (49.76) | 308 (45.50) | 0.003 |
| TOAST | <0.001 | |||
| Large-artery atherosclerosis, n (%) | 180 (32.79) | 248 (40.19) | 251 (37.08) | |
| Small-artery occlusion, n (%) | 92 (16.28) | 100 (16.21) | 172 (25.41) | |
| Cardio-embolism, n (%) | 88 (15.58) | 89 (14.42) | 46 (6.79) | |
| Undetermined etiology, n (%) | 33 (5.84) | 23 (3.73) | 25 (3.69) | |
| Other etiology, n (%) | 172 (30.44) | 157 (25.45) | 183 (27.03) | |
| Laboratory tests | ||||
| Hemoglobin, g/L, mean (SD) | 136.95 ± 21.31 | 140.13 ± 19.98 | 142.84 ± 19.88 | 0.143 |
| platelet count, ^109/L, mean (SD) | 178.18 ± 84.69 | 180.48 ± 69.38 | 177.95 ± 67.73 | <0.001 |
| Creatinine, mg/dL, mean ± SD | 75.79 ± 41.86 | 79.22 ± 35.24 | 84.52 ± 64.49 | <0.001 |
| Uric acid, μmol/L, mean ± SD | 297.82 ± 93.66 | 312.86 ± 101.70 | 326.08 ± 109.74 | <0.001 |
| HDL, mmol/L, mean ± SD | 1.32 ± 0.39 | 1.20 ± 0.40 | 1.12 ± 0.40 | 0.900 |
| LDL, mmol/L, mean ± SD | 2.14 (1.62–2.7) | 2.49 (1.92–3.1) | 2.79 (2.15–3.42) | <0.001 |
| Total cholesterol, mmol/L, mean ± SD | 3.81 (3.22–4.44) | 4.22 (3.59–4.89) | 4.76 (4.06–5.47) | <0.001 |
| Glucose, mmol/L, mean ± SD | 5.32 ± 1.15 | 6 ± 1.36 | 8.58 ± 4.46 | 0.001 |
| Triglyceride, mmol/L, median (Q1–Q3) | 0.89 (0.73–1.03) | 1.38 (1.17–1.59) | 2.21 (1.78–2.79) | <0.001 |
| TGI, (mg/dL)2, mean ± SD | 8.17 ± 0.29 | 8.76 ± 0.15 | 9.58 ± 0.53 | <0.001 |
| Therapy after admission | ||||
| Antiplatelet, n (%) | 535 (94.69) | 584 (94.65) | 650 (96.01) | 0.343 |
| Thrombolysis, n (%) | 11 (1.95) | 14 (2.27) | 15 (2.22) | 0.940 |
| Anticoagulation, n (%) | 48 (8.50) | 35 (5.67) | 21 (3.10) | <0.001 |
SBP, systaltic blood pressure; DBP, diastolic blood pressure; SD, standard deviation. *The range of MHR and the number of patients in each tertile.