Table 2.
Variables | T1 (4.98–8.50) | T2 (8.50–9.04) | T3 (9.04–12.91) | p-value |
---|---|---|---|---|
N | 682 | 614 | 565 | – |
Age, years, mean (SD) | 75.02 ± 6.79 | 74.26 ± 6.21 | 74.06 ± 6.21 | 0.020 |
Male, n (%) | 504 (73.90) | 364 (59.28) | 314 (55.58) | <0.001 |
Baseline NIHSS score, median (Q1–Q3) | 5 (2–11) | 5 (2–11) | 5 (2–11) | 0.800 |
Time from onset to admission, hour, median (Q1–Q3) | 48 (24–96) | 48 (20–108) | 48 (20–96) | 0.682 |
Hypertension, n (%) | 502 (73.61) | 481 (78.34) | 493(87.26) | <0.001 |
Diabetes, n (%) | 92 (13.49) | 162 (26.38) | 321 (56.81) | <0.001 |
Atrial fibrillation, n (%) | 149 (21.85) | 144 (23.45) | 120 (21.24) | 0.598 |
Rheumatic heart disease, n (%) | 41 (6.01) | 41 (6.68) | 31 (5.49) | 0.701 |
Coronary heart disease, n (%) | 64 (9.38) | 76 (12.38) | 73 (12.92) | 0.116 |
History of stroke, n (%) | 145 (21.26) | 134 (21.82) | 101 (17.88) | 0.166 |
Drinking, n (%) | 151 (22.14) | 115 (18.73) | 95 (16.81) | 0.051 |
Smoking, n (%) | 197 (28.89) | 154 (25.08) | 138 (24.42) | 0.144 |
TOAST | 0.763 | |||
Large-artery atherosclerosis, n (%) | 191 (28.01) | 195 (31.76) | 163 (28.85) | |
Small-artery occlusion, n (%) | 129 (18.91) | 108 (17.59) | 119 (21.06) | |
Cardio-embolism, n (%) | 146 (21.41) | 133 (21.66) | 112 (19.82) | |
Undetermined etiology, n (%) | 10 (1.47) | 7 (1.14) | 8 (1.16) | |
Other etiology, n (%) | 206 (30.21) | 171 (27.85) | 163 (28.85) | |
Laboratory tests | ||||
Hemoglobin, g/L, mean (SD) | 130.16 ± 19.44 | 131.54 ± 18.26 | 131.30 ± 15.57 | 0.215 |
Platelet count, ^109/L, mean (SD) | 160.63 ± 76.65 | 166.24 ± 68.87 | 163.29 ± 63.35 | <0.001 |
Creatinine, mg/dL, mean ± SD | 85.75 ± 43.25 | 86.87 ± 44.73 | 91.50 ± 50.02 | <0.001 |
Uric acid, μmol/L, mean ± SD | 296.98 ± 102.07 | 309.89 ± 105.75 | 318.46 ± 110.00 | 0.175 |
HDL, mmol/L, mean ± SD | 1.43 ± 0.42 | 1.32 ± 0.42 | 1.17 ± 0.36 | <0.001 |
LDL, mmol/L, mean ± SD | 2.08 (1.58–2.60) | 2.45 (1.91–3.01) | 2.62 (1.98–3.21) | <0.001 |
Total cholesterol, mmol/L, mean ± SD | 3.82 (3.28–4.48) | 4.25 (3.62–4.93) | 4.52 (3.68–5.20) | <0.001 |
Glucose, mmol/L, mean ± SD | 5.48 ± 1.35 | 6.58 ± 1.73 | 99.84 ± 5.71 | <0.001 |
Triglyceride, mmol/L, median (Q1–Q3) | 0.85 (0.69–1.00) | 1.26 (1.04–1.49) | 1.89 (1.48–2.49) | <0.001 |
TGI, (mg/dL)2, mean ± SD | 8.15 ± 0.33 | 8.76 ± 0.15 | 9.56 ± 0.49 | <0.001 |
Therapy after admission | ||||
Antiplatelet, n (%) | 640 (93.84) | 581 (94.62) | 535 (94.69) | 0.761 |
Thrombolysis, n (%) | 22 (3.23) | 17 (2.77) | 17 (3.01) | 0.893 |
Anticoagulation, n (%) | 36 (5.28) | 34 (5.54) | 29 (5.13) | 0.951 |
SBP, systaltic blood pressure; DBP, diastolic blood pressure; SD, standard deviation. *The range of MHR and the number of patients in each tertile.