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. 2023 Aug 3;14:1198487. doi: 10.3389/fneur.2023.1198487

Table 2.

Baseline characteristics of included patients grouped by low and high TGI group in patients older than 65 years old.

Variables T1 (4.98–8.50) T2 (8.50–9.04) T3 (9.04–12.91) p-value
N 682 614 565
Age, years, mean (SD) 75.02 ± 6.79 74.26 ± 6.21 74.06 ± 6.21 0.020
Male, n (%) 504 (73.90) 364 (59.28) 314 (55.58) <0.001
Baseline NIHSS score, median (Q1–Q3) 5 (2–11) 5 (2–11) 5 (2–11) 0.800
Time from onset to admission, hour, median (Q1–Q3) 48 (24–96) 48 (20–108) 48 (20–96) 0.682
Hypertension, n (%) 502 (73.61) 481 (78.34) 493(87.26) <0.001
Diabetes, n (%) 92 (13.49) 162 (26.38) 321 (56.81) <0.001
Atrial fibrillation, n (%) 149 (21.85) 144 (23.45) 120 (21.24) 0.598
Rheumatic heart disease, n (%) 41 (6.01) 41 (6.68) 31 (5.49) 0.701
Coronary heart disease, n (%) 64 (9.38) 76 (12.38) 73 (12.92) 0.116
History of stroke, n (%) 145 (21.26) 134 (21.82) 101 (17.88) 0.166
Drinking, n (%) 151 (22.14) 115 (18.73) 95 (16.81) 0.051
Smoking, n (%) 197 (28.89) 154 (25.08) 138 (24.42) 0.144
TOAST 0.763
Large-artery atherosclerosis, n (%) 191 (28.01) 195 (31.76) 163 (28.85)
Small-artery occlusion, n (%) 129 (18.91) 108 (17.59) 119 (21.06)
Cardio-embolism, n (%) 146 (21.41) 133 (21.66) 112 (19.82)
Undetermined etiology, n (%) 10 (1.47) 7 (1.14) 8 (1.16)
Other etiology, n (%) 206 (30.21) 171 (27.85) 163 (28.85)
Laboratory tests
Hemoglobin, g/L, mean (SD) 130.16 ± 19.44 131.54 ± 18.26 131.30 ± 15.57 0.215
Platelet count, ^109/L, mean (SD) 160.63 ± 76.65 166.24 ± 68.87 163.29 ± 63.35 <0.001
Creatinine, mg/dL, mean ± SD 85.75 ± 43.25 86.87 ± 44.73 91.50 ± 50.02 <0.001
Uric acid, μmol/L, mean ± SD 296.98 ± 102.07 309.89 ± 105.75 318.46 ± 110.00 0.175
HDL, mmol/L, mean ± SD 1.43 ± 0.42 1.32 ± 0.42 1.17 ± 0.36 <0.001
LDL, mmol/L, mean ± SD 2.08 (1.58–2.60) 2.45 (1.91–3.01) 2.62 (1.98–3.21) <0.001
Total cholesterol, mmol/L, mean ± SD 3.82 (3.28–4.48) 4.25 (3.62–4.93) 4.52 (3.68–5.20) <0.001
Glucose, mmol/L, mean ± SD 5.48 ± 1.35 6.58 ± 1.73 99.84 ± 5.71 <0.001
Triglyceride, mmol/L, median (Q1–Q3) 0.85 (0.69–1.00) 1.26 (1.04–1.49) 1.89 (1.48–2.49) <0.001
TGI, (mg/dL)2, mean ± SD 8.15 ± 0.33 8.76 ± 0.15 9.56 ± 0.49 <0.001
Therapy after admission
Antiplatelet, n (%) 640 (93.84) 581 (94.62) 535 (94.69) 0.761
Thrombolysis, n (%) 22 (3.23) 17 (2.77) 17 (3.01) 0.893
Anticoagulation, n (%) 36 (5.28) 34 (5.54) 29 (5.13) 0.951

SBP, systaltic blood pressure; DBP, diastolic blood pressure; SD, standard deviation. *The range of MHR and the number of patients in each tertile.