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. 2023 Aug 17;12:RP87283. doi: 10.7554/eLife.87283

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© 2023, Yan, Xiong, Zhou et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

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Figure 4. — Co-immunoprecipitation analyses of T47D cells (a) and 293T cells (b) transfected with Vector (Vec), METTL3-WT or its mutants. (c) Immunoblot analysis of 293T cells infected with or without lentivirus encoding METLL3 shRNA. (d) Immunoblot of whole cell extracts (WCE) and immunoprecipitations (IP) of 293T cells infected with lentivirus encoding METLL3 shRNA followed by transfection with METTL3-WT-Flag, METTL3-Δ238-Flag combining with or without METTL3a (no flag tag), or control vector as indicated.

Figure 4—source data 1. Unedited western blot images for Figure 4.

elife-87283-fig4-data1.pdf^{(1.4MB, pdf)}