Table 4. The Na +and K+conductances intentionally do not match the reference because models with passive dendrite need higher current input to initiate action potentials (Levine and Woody, 1978).

Therefore, we set it to achieve the desired amplitude on the dendrite and the dendritic spine according to the predictions of Golding et al., 2001 and Kwon et al., 2017.

Name	Value	Reference
Soma parameters for Na +and K+ channel
Sodium conductance	${\gamma }_{Na}=8\cdot {10}^{2}nS$	generic value, see legend commentary
Potassium conductance	${\gamma }_K=40nS$	generic value, see legend commentary
Reversal potential sodium	$Ere{v}_{Na}=50mV$	Migliore et al., 1999
Reversal potential potassium	$Ere{v}_K=-90mV$	Migliore et al., 1999
BaP attenuation parameters
Attenuation step factor (age)	${\delta }_{age}$	see Equation 7 and Figure 9b and c bottom Buchanan and Mellor, 2007; Golding et al., 2001
Attenuation step factor	${\delta }_{decay}=1.727\cdot {10}^{-5}$	adjusted to fit Buchanan and Mellor, 2007; Golding et al., 2001
Auxiliary attenuation step factor	${\delta }_{aux}=2.304\cdot {10}^{-5}$	adjusted to fit Buchanan and Mellor, 2007; Golding et al., 2001
Recovery time for the attenuation factor	${\tau }_{rec}=2s$	adjusted to fit Buchanan and Mellor, 2007; Golding et al., 2001
Recovery time for the age attenuation factor	${\tau }_{rec}^{age}=0.5s$	adjusted to fit Buchanan and Mellor, 2007; Golding et al., 2001
AP evoked by EPSP
Decay time for $V_{evoke}$	${\tau }_V=0.04s$	Hines and Carnevale, 1997
Delay AP evoked by EPSP	${\delta }_{delay-AP}=0.015s$	Fricker and Miles, 2000