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. 2023 Aug 10;2023:8537693. doi: 10.1155/2023/8537693

Table 2.

Cross-sectional associations (Pearson's correlation coefficients) between plasma concentrations of AGE/oxidation-P and eGFR, during gestation and prior to the onset of preeclampsia.

DM+PE+ DM+PE- DM-
R p value R p value R p value
Nε-(Carboxymethyl)lysine (CML) V1 -0.29 0.20 -0.500 0.018 0.00 0.99
V2 -0.30 0.17 0.18 0.43 0.05 0.86
V3 -0.483 0.023 0.06 0.78 0.24 0.33

Carboxyethyl-lysine (CEL) V1 -0.16 0.48 -0.06 0.80 -0.45 0.07
V2 -0.463 0.030 -0.05 0.82 0.01 0.98
V3 -0.495 0.019 0.04 0.85 -0.01 0.97

Methylglyoxal-hydroimidazolone (MGH1) V1 0.05 0.84 -0.14 0.54 -0.552 0.022
V2 -0.497 0.019 0.22 0.35 0.34 0.17
V3 -0.429 0.046 0.08 0.70 -0.08 0.75

3-Deoxyglucosone hydroimidazolones (3DGH) V1 -0.12 0.61 -0.12 0.59 -0.40 0.12
V2 -0.43 0.06 -0.05 0.82 0.34 0.16
V3 -0.43 0.05 -0.08 0.73 -0.18 0.47

Glyoxal-hydroimidazolone (GH1) V1 -0.12 0.60 -0.32 0.14 -0.632 0.006
V2 -0.512 0.015 0.07 0.78 0.02 0.94
V3 -0.663 0.001 -0.08 0.72 0.14 0.56

Methionine sulfoxide (MetSO) V1 -0.10 0.67 0.34 0.12 -0.22 0.40
V2 0.01 0.97 0.26 0.25 0.37 0.13
V3 -0.38 0.09 -0.02 0.94 0.20 0.42

2-Aminoadipic acid (2-AAA) V1 0.00 0.99 0.28 0.21 -0.20 0.44
V2 -0.26 0.24 0.34 0.13 0.552 0.018
V3 -0.41 0.06 0.16 0.46 0.01 0.98

Data are presented as the Pearson correlation coefficient, p value. Boldface indicates p values < 0.05 (statistically significant). Each AGE product and oxidation product is corrected by total protein concentration. Units for all: nmol/g.