Table 7.
Group | Dose (mg/kg) | % parasitemia (mean ± SEM) | % suppression | Mean survival time (days) | |
---|---|---|---|---|---|
D3 | D7 | ||||
DW | 10 ml/kg | 49.89 ± 1.84 | 56.65 ± 3.19 | 0 | 6.17 ± 0.31 |
CQ | 25 | 48.59 ± 2.25 | 0.03 ± 0.01a3 | 99.95a3 | 30.00 ± 0.00a3 |
SM | 100 | 50.43 ± 3.29 | 45.20 ± 2.75a2b3d1 | 20.23a2b3 | 6.83 ± 0.31b3 |
SM | 200 | 47.07 ± 1.49 | 43.41 ± 1.17a2b3 | 23.38a2b3 | 7.50 ± 0.22a2b3 |
SM | 400 | 47.83 ± 0.99 | 36.36 ± 1.7a3b3c1 | 35.82a3b3c1 | 7.67 ± 0.21a2b3 |
Data are expressed as mean ± SEM (n = 6); CQ = chloroquine; DW = distilled water; D3 = day 3; D7 = day7; SM = Silene macrosolen; a = compared to the negative control; b = compared to the positive control; c = compared to 100 mg/kg crude extract; d = compared to 400 mg/kg crude extract; 1 = P < 0.05; 2 = P < 0.01; 3 = P < 0.001.