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. 2023 Aug 8;27(5):553–561. doi: 10.1007/s40291-023-00668-9
Single-cell sequencing enables profiling of cellular heterogeneity within a tissue.
Vulnerability of specific cell types is a hallmark of neurodegenerative diseases and can be addressed by this technology.
This review provides a summary of the recent knowledge in Parkinson’s, Alzheimer’s, Huntington’s disease, and multiple sclerosis, acquired through single-cell sequencing.