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. 2023 Aug 17;14:4997. doi: 10.1038/s41467-023-40719-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Spearman correlation between median genome-wide nucleotide diversity and relative abundance of Gardnerella spp. along pregnancy. The line and the shaded area depict the best-fit trendline and the 95% confidence interval (mean ± 1.96 s.e.m.) of the linear regression. b, c Predicted maximal doubling time (gRodon³⁶) of Gardnerella spp. compared between sPTB and TB, displayed for the first (b, S1) and second (c, S2) halves of pregnancy. d, e Median D’ of Gardnerella spp compared between sPTB and TB, displayed for the first (S1, d) and second (S2, e) halves of pregnancy. Lower D’ indicates more frequent recombination. f dN/dS of Gardnerella spp genes compared between sPTB and TB by COG functional categories, displayed for the second half of pregnancy (S2). dN/dS closer to 0 indicates stronger purifying selection. N = 40 and 135 for sPTB and TB, respectively, included in this panel. Box, IQR; line, median; whiskers, 1.5*IQR; p, two-sided Mann-Whitney.