Fig. 3.

Change in haematological parameters and PROs Mean change values and 95% CI (whiskers) at follow-up timepoints versus baseline with all available samples in the intention-to-treat population included. Changes were assessed and analysed using the restricted maximum likelihood-based MMRM described in the methods section. Number of women contributing with data is given at the bottom. Asterisks indicate significant between-group differences and significance level: *p < 0.05; **p = 0.001–0.01; ***p < 0.001. CI confidence interval, FACIT functional assessment of chronic illness therapy, IV intravenous, MCS mental component summary, PCS physical component summary, MMRM mixed model repeated measures