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. 2023 Aug 3;14:1231276. doi: 10.3389/fimmu.2023.1231276

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Copyright © 2023 Motsoeneng, Manamela, Kaldine, Kgagudi, Hermanus, Ayres, Makhado, Moyo-Gwete, van der Mescht, Abdullah, Boswell, Ueckermann, Rossouw, Madhi, Moore and Richardson

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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People living with HIV have delayed humoral response kinetics following SARS-CoV-2 D614G infection. Fold changes in autologous antibody responses a week after admission during SARS-CoV-2 D614G or Beta infection in PWOH (D614G, n = 27; Beta, n = 9) shown in blue and for PLWH (D614G, n = 10; Beta, n = 5) shown in red. The dotted line indicates no change between sampling time points, above 1 indicates an increase in function and below 1 indicates a decrease in function. The median of the fold changes is indicated by solid lines. For each of the antibody responses Kruskal-Wallis test with Dunn’s correction was calculated for multiple test comparison. Statistical significance: **p < 0.01; *p < 0.05.