Figure 4.

People living with HIV have durable humoral responses following ChAdOx1 nCoV-19 vaccination. (A) Thirty participants received two doses of the ChAdOx1 nCoV-19 vaccine, antibody responses were assessed for days 28, 42, and 182 post-vaccinations when plasma samples were collected from PWOH (n = 17) shown in blue and PLWH (n = 13) shown in red. (B) Neutralization of D614G pseudovirus, (C) ADCP scores, (D) IgG binding by ELISA, and (E) ADCC FcγRIIIa signalling were measured. The lines represent the medians with error bars, indicating standard deviation of participant data. Mann Whitney U test was calculated to compare groups at each of the time points. Statistical significance: **p < 0.01; *p < 0.05; ns, not significant.