Table 1.

Proteins translated by weak mRNAs.

Name	Function
Cyclin D1	It makes cells in G1 phase enter S phase by allosteric regulation (17).
c-Myc	It promotes cell cycle progression, transforming cells in G1 phase into S phase, and regulates cell apoptosis (18).
FGF2	Exogenous FGF2 is activated by binding to tyrosine kinase receptors of FGFRs, which leads to cell proliferation or migration, and endogenous FGF2 can be anti-apoptotic by binding to apoptosis inhibitor 5 (API5) (19).
VEGF	It stimulates endothelial cell proliferation and new blood vessel formation (20).
ODS	As a rate-limiting enzyme in polyamine synthesis, it regulates cell proliferation, apoptosis and senescence (21).
Bcl-2	Associated with chromosomal translocations, it can inhibit cell death (22).
Survivin	It has no enzymatic activity and helps to align the chromosomes correctly during mitotic metaphase. As one of the human inhibitors of apoptosis (IAP), it interacts with XIAP to inhibit apoptosis, and can also regulate mitochondrial dynamics and affect cell metabolism (23).
bFGF	It preserves the viability of epithelial cells, endothelial cells, smooth muscle cells and nerve cells, and inhibits their apoptosis (24).