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Pattern
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FFR
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NHPR
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FCA
|
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Focal
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FFR ≤0.80 at distal segment, abrupt single point of pressure loss.
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iFR/RFR/DFR ≤0.89 at distal segment, with abrupt single point of ≥0.03 index units over ≤15 mm segment.
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QFR/vFFR/FFRCT ≤0.80 at distal segment, with single region of pressure loss of>0.05 in <10 mm segment.
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|
Tandem
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FFR ≤0.80 at distal segment, presence of ≥2 abrupt change of FFR values.
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iFR/RFR/DFR ≤0.89, at distal segment, with presence of ≥2 abrupt changes of index values.
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QFR/vFFR/FFRCT ≤0.80 at distal vessel with presence of ≥2 abrupt changes of pressure loss.
|
|
Diffuse*
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FFR ≤0.80 at distal segment with progressive and linear loss in FFR values over length of vessel.
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iFR/RFR/DFR ≤0.89 at distal segment, with progressive and linear loss in pressure over length of vessel during iFR pullback.
|
Progressive and linear loss in QFR/vFFR/FFRCT values over length of vessel during longitudinal analysis.
|
|
Post-PCI physiology assessments
|
|
Pattern
|
FFR
|
NHPR
|
FCA
|
|
Focal
|
FFR with abrupt pressure loss at the stented site or elsewhere within the treated vessel.
|
Abrupt drop of iFR/RFR/DFR values at the stented site or elsewhere within the treated vessel.
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Abrupt drop of QFR/vFFR values at the stented site or elsewhere within the treated vessel.
|
|
Tandem
|
Abrupt drop of FFR values at the level of an untreated tandem stenosis.
|
Abrupt drop of iFR/RFR/DFR values at the level of an untreated tandem stenosis.
|
Abrupt drop of QFR/vFFR values at the level of an untreated tandem stenosis.
|
|
Diffuse*
|
Progressive and linear loss in FFR values over length of stented vessel during pullback.
|
Progressive and linear loss in iFR/RFR/DFR values over length of stented vessel during pullback.
|
Progressive and linear loss in QFR/vFFR values over length of stented vessel.
|
|
*These criteria are clinical consensus statements and further validation is warranted. DFR: diastolic hyperaemia-free ratio; FCA: functional coronary angiography; FFR: fractional flow reserve; FFRCT: computed tomography-derived FFR; iFR: instantaneous wave-free ratio; NHPR: non-hyperaemic pressure ratio; PCI: percutaneous coronary intervention; QFR: quantitative flow ratio; RFR: resting full-cycle ratio; vFFR: virtual FFR
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