Table 2.

Model performance estimates on retrospective and prospectively collected test sets for all twelve models

Model performance		Positive (abnormal) prevalence		AUROC
Diagnostic	Component	Retrospective	Prospective	Retrospective	Prospective
CBC with differential	Hematocrit	0.47 [0.45, 0.49]	0.43 [0.42, 0.44]	0.86 [0.85, 0.88]	0.83 [0.83, 0.84]
	Hemoglobin	0.50 [0.48, 0.52]	0.47 [0.46, 0.47]	0.88 [0.86, 0.89]	0.83 [0.83, 0.84]
	Platelets	0.26 [0.24, 0.28]	0.21 [0.21, 0.22]	0.79 [0.77, 0.82]	0.77 [0.76, 0.78]
	White blood cell	0.29 [0.27, 0.31]	0.27 [0.27, 0.28]	0.76 [0.74, 0.79]	0.69 [0.68, 0.70]
Metabolic panel	Albumin	0.20 [0.18, 0.21]	0.21 [0.20, 0.21]	0.88 [0.86, 0.91]	0.85 [0.84, 0.86]
	Blood urea nitrogen	0.22 [0.20, 0.24]	0.24 [0.23, 0.25]	0.85 [0.83, 0.87]	0.80 [0.79, 0.81]
	Calcium	0.11 [0.10, 0.13]	0.11 [0.11, 0.12]	0.80 [0.76, 0.83]	0.79 [0.78, 0.81]
	Carbon dioxide	0.16 [0.14, 0.17]	0.20 [0.20, 0.21]	0.69 [0.66, 0.72]	0.62 [0.61, 0.63]
	Creatinine	0.31 [0.29, 0.33]	0.32 [0.31, 0.33]	0.78 [0.75, 0.80]	0.75 [0.74, 0.76]
	Potassium	0.06 [0.05, 0.08]	0.08 [0.08, 0.09]	0.67 [0.61, 0.72]	0.60 [0.59, 0.62]
	Sodium	0.12 [0.10, 0.13]	0.17 [0.16, 0.17]	0.79 [0.75, 0.82]	0.71 [0.70, 0.72]
Magnesium	Magnesium	0.15 [0.14, 0.17]	0.14 [0.13, 0.15]	0.70 [0.67, 0.73]	0.65 [0.63, 0.67]

AUROC: area under the receiver operating characteristics curve; CBC: complete blood count.