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. 2023 Aug 3;145(32):17632–17642. doi: 10.1021/jacs.3c03338

Figure 3.

Figure 3

(A) Chemoenzymatic radiosyntheses of [18F]FDT, [18F]FDL, [18F]FDC, [18F]FDM, and [18F]FSK from [18F]FDG. All reactions were carried out at 37 °C, stirring for 20 min, using 6 mg (0.020 mmol) of precursor, 0.3 mg of enzyme (3–6 units), and 10–15 mCi [18F]FDG in 0.5 mL of citrate buffer (0.1 M, pH = 6.0). (B) Radio HPLC analysis of each enzymatic reaction using a YMC-Pack Polyamine II column.