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. 2023 Aug 4;13:1155592. doi: 10.3389/fonc.2023.1155592

Table 2.

Analyses of patients’ characteristics after four treatment cycles.

Characteristic Control group (n=30) JK-5G group (n=30) t/χ2 /Z P
PG-SGA score—no.(%) 11.05 0.004 b
 0–1 13 (43.33%) 25 (83.33%)
 2–8 14 (46.67%) 5 (16.67%)
 ≥9 3 (10.00%) 0
NRS score—no.(%) 3.07 0.143 b
 No pain (0) 19 (63.33%) 25 (83.33%)
 Mild pain (1-3) 11 (36.67%) 5 (16.67%)
 Moderate pain (4–6) 0 0
 Severe pain (7-10) 0 0
Assessment of mood symptoms
HADS
Anxiety subscale (HADS-A) 1.70±1.60 1.03±0.89 1.99 0.052 a
Depression subscale (HADS-D) 1.47±1.74 0.20±0.61 3.77 <0.01 a
PHQ-9
Depression severity
7.93 0.005 b
 No (0-4) 23 (76.67%) 30 (100%)
 Mild (5-9) 7 (23.33%) 0 (0%)
 Moderate(10-14) 0 0

Data are means ±SD or n (%). PG-SGA, Patient-Generated Subjective Global Assessment; NRS, Numerical Rating Scale; HADS, Hospital Anxiety and Depression Scale; PHQ-9, Patient Health Questionnaire-9.

a

p-values calculated with the independent-samples Student’s t-tests for continuous variables.

b

p-values calculated with two-sided χ2 and Fisher’s exact tests for categorical variables.