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. 2023 Aug 3;14:1218059. doi: 10.3389/fphar.2023.1218059

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Copyright © 2023 Pi, Zeng, Zeng, Han, Bai and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic representation of the molecular mechanism of COVID-19-induced EMT. Angiotensin-converting enzyme 2 (ACE2); Transmembrane serine protease 2 (TMPRSS2); Transforming growth factor-β (TGF-β); Transforming growth factor-β1 (TGF-β1); Interleukin-8 (IL-8); Interleukin-6 (IL-6); Interleukin-1β (IL-1β); Neutrophil gelatinase-associated lipocalin (NGAL); Protease-activated receptor 4 (PAR 4); Zinc-finger E-box-binding 1 (ZEB1); Urokinase-type plasminogen activator receptor (uPAR); Urokinase plasminogen activator (uPA); Anexelekto (AXL).