TABLE 2.

Genotypes of viable pups derived from Dnmt1 ^P/+ x Dnmt1 ^P/+ matings. p values were calculated using a chi-square goodness of fit test based on the 1:2:1 Mendelian genotype ratio expected from heterozygous parents vs. the expected 1:2 ratio for a recessive lethal.

Days post-partum	+/+	P/+	P/P	p-Value (1:2:1)	p-Value (1:2)
P21-28	84	158	0	2.65 × 10−18	0.6494