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. 2023 Aug 4;11:1252706. doi: 10.3389/fbioe.2023.1252706

TABLE 1.

Comparison of physical, chemical, and biological modifications of BC.

Modification method Advantage Disadvantage References
Physical modification Synthesis means are simple and gentle (adsorption, ultrasonication, and coating) Chemical structure of BC is maintained; applications of BC are decided by added materials Qian et al. (2023)
Chemical modification Easily introduced functional groups into the BC structure by esterification, etherification, grafting, or oxidation Complex operation process; expensive approach; tedious and delicate reaction procedures Gao et al. (2019)
Singhsa et al. (2018)
Biological modification Easy processing Suspended particles with quick penetration lead to difficult composite synthesis Andriani et al. (2020)
Multiple synthesis methods Limited applications of BC via the agitation culture method Shavyrkina et al. (2021)
Basic structure of BC is disturbed Luo et al. (2020)