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. 2023 Aug 4;14:1176204. doi: 10.3389/fpsyg.2023.1176204

Table 2.

Summary of the main results of the study group.

Before-O3T median (Q1–Q3) After-O3T median (Q1–Q3) p-value
HADS-A (from 0 to 21) 6.5 (3–10.8) 3.5 (2–6.8) 0.003
HADS-D (from 0 to 21) 4 (1.3–9) 3.5 (0.3–5) 0.022
EQ-5D-5L: Anxiety/depression (from 1 to 5) 1.5 (1–3) 1 (1–2) 0.047
EQ-5D-5L: EQ VAS (from 0 to 100) 52.5 (43–78) 75 (60–90) 0.015
Before-O3T Correlations (rho) After-O3T Correlations (rho) p-value before/after
HADS-A-EQ-5D-5L Anxiety/Depression-EQ-5D-5L, EQ VAS 0.866, –0.554 0.874, –0.627 < 0.001/< 0.001
0.026/0.009
HADS-D-EQ-5D-5L Anxiety/Depression-EQ-5D-5L, EQ VAS 0.852, –0.644 0.673, –0.812 < 0.001/0.004
0.007/<0.001

O3T, ozone therapy; Q1–Q3: quartiles 1 and 3; HADS, Hospital Anxiety and Depression Scale; HADS-A, HADS-Anxiety; HADS-D, HADS-Depression; EQ VAS, EQ-5D-5L Visual Analog Scale self-perceived general health status.