Table 5. Taxa reported by various differential abundance methods throughout our analysis.
| Taxonomic Level | Taxon | Algorithm | Control/ADHD | Effect Size and p-value |
|---|---|---|---|---|
| Family | Clostridiaceae 1 | ALDEx2 | Control | EFF = 7.90, p = 0.016 |
| Genus | Coprobacillus | DESeq2 | ADHD | LFC = 2.00, p = 0.044 |
| Genus | Odoribacter | LEfSe | ADHD | LDA = 2.68, p = 0.027 |
| Genus | Turicibacter | LEfSe | Control | LDA = 3.04, p = 0.028 |
| DESeq2 | LFC = 2.12, p = 0.007 | |||
| ALDEx2 | EFF = 1.75, p = 0.033 | |||
| Genus | Haemophilus parainfluenzae | DESeq2 | Control | LFC = 0.572, p = 0.042 |
| Genus | Butyricimonas | LEfSe | ADHD | LDA = 2.37, p = 0.019 |
| ALDEx2 | EFF = 3.15, p = 0.032 | |||
| Lowest Possible | V. dispar | LEfSe | ADHD | LDA = 2.31, p = 0.039 |
Taxa reported as elevated by various differential abundance methods, when comparing Control vs ADHD, and further broken down by subscale. LDA = Linear Discriminant Analysis effect size (for LEfSe), LFC = Log Fold Change (for DESeq2), EFF = Effect Size (for ALDEx2).