Table 1.

General Characteristics, Plasma Levels of ADAM 8, in Children with ASD and Healthy Controls and Their Association with ASD Severity

	Age (Years) Median (IQ Range)	ADAM8 pg/mL Median (IQ Range)	p-value*	CARS Score
Children with ASD, n = 37 (34 male+ 03 female)	6 (3–12)	4683 (2885–5229)	<0.01*	> 30
Children with severe ASD (n =21)	--	4663 (4060–5000)	<0.05* 0.71	> 36.5
Children with mild to moderate ASD (n =16)	--	4632 (2885–5229)	<0.01*	< 36.5
Healthy children, n= 40 (25 male + 15 female)	11 (3–13) p= <0.05*	5000 (4047–5000)	<0.05*

Notes: *Comparing ASD children with control subjects (p-value ≤ 0.05 was considered statistically significant).