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. 2023 Aug 7;120(33):e2220472120. doi: 10.1073/pnas.2220472120

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Copyright © 2023 the Author(s). Published by PNAS.

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Fig. 3. — SETD7 expression is significantly increased in CRPC. (A) Box plots for SETD7 expression (ratio to a panel of housekeeping genes) in normal and primary PCa samples (TCGA) and mCRPC samples (SU2C). (B) Kaplan–Meier curve for the overall survival in PCa tumors with higher SETD7 expression (red, the top 25%) versus with lower expression (blue, the bottom 25%). (C) SETD7 mRNA expression in LNCaP cells progressing on ADTs (public dataset, GSE8702). (D) SETD7 mRNA expression in paired VCaP xenografts biopsy at androgen-dependent stage (AD), 4 d after castration (CS), and relapsed tumors (CRPC) (public dataset, GSE31410).