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. 2023 Aug 4;14:1229112. doi: 10.3389/fneur.2023.1229112

Table 1.

Overview of the FcRn receptors.

Agent Company Molecule Current status
Efgartigimod ARGENX Humanized IgG1 Fc Fragment Approved for treatment of AChR+ gMG
Rozanolixizumab UCB Humanized IgG4 Monoclonal Phase 3 completed
Nipocalimab Johnson and Johnson Humanized aglycosylated monoclonal ab Phase 3 study ongoing
Batoclimab Immunovant Humanized IgG1 monoclonal ab Phase 3 study ongoing
ABY-039 Affibody Bilvalent antibody Phase 1 study was prematurely terminated