Table 2.
Multivariate Cox regression for CDSS score on 60-day mortality of AML
| Variable | Non-adjusted Model | Model I | Model II | Model III | ||||
|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | |
| CDSS score | 1.39 (1.25 ~ 1.54) | < 0.001 | 1.39 (1.25 ~ 1.54) | < 0.001 | 1.26 (1.06 ~ 1.49) | 0.009 | 1.27 (1.01 ~ 1.61) | 0.045 |
| Binary variable | ||||||||
| CDSS score < 6 | Ref | Ref | Ref | Ref | ||||
| CDSS score ≥ 6 | 2.89 (1.91 ~ 4.38) | < 0.001 | 2.77 (1.82 ~ 4.20) | < 0.001 | 2.58 (1.36 ~ 4.88) | 0.004 | 2.98 (1.24 ~ 7.19) | 0.013 |
Model I: Adjusts for sex + age; Model II: adjusts for Model I + FAB subtype + bleeding + prognostic stratification + Pulmonary infection + chemotherapy; Model III: adjusts for Model II + BM blast + AT + ALB + Crea + HDL + TG + Glu + CK-MB + Myo + SF + WBC. Dummy variables were used for SF; WBC was entered as a categorical variable
CDSS Chinese DIC scoring system, DIC disseminated intravascular coagulation, WBC,white blood cell, BM bone marrow, FAB French, American, British, AT antithrombin, Alb albumin, Crea creatinine, HDL high-density lipoprotein, Glu glucose, CK creatine kinase, CK-MB creatine kinase isoenzyme MB, SF serum ferritin, Myo myoglobin, HR hazard ratio, CI confidence interval