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. 2023 Jun 23;56(3):423–432. doi: 10.1007/s11239-023-02850-6

Table 2.

Multivariate Cox regression for CDSS score on 60-day mortality of AML

Variable Non-adjusted Model Model I Model II Model III
HR (95% CI) P-value HR (95% CI) P-value HR (95% CI) P-value HR (95% CI) P-value
CDSS score 1.39 (1.25 ~ 1.54)  < 0.001 1.39 (1.25 ~ 1.54)  < 0.001 1.26 (1.06 ~ 1.49) 0.009 1.27 (1.01 ~ 1.61) 0.045
Binary variable
 CDSS score < 6 Ref Ref Ref Ref
 CDSS score ≥ 6 2.89 (1.91 ~ 4.38)  < 0.001 2.77 (1.82 ~ 4.20)  < 0.001 2.58 (1.36 ~ 4.88) 0.004 2.98 (1.24 ~ 7.19) 0.013

Model I: Adjusts for sex + age; Model II: adjusts for Model I + FAB subtype + bleeding + prognostic stratification + Pulmonary infection + chemotherapy; Model III: adjusts for Model II + BM blast + AT + ALB + Crea + HDL + TG + Glu + CK-MB + Myo + SF + WBC. Dummy variables were used for SF; WBC was entered as a categorical variable

CDSS Chinese DIC scoring system, DIC disseminated intravascular coagulation, WBC,white blood cell, BM bone marrow, FAB French, American, British, AT antithrombin, Alb albumin, Crea creatinine, HDL high-density lipoprotein, Glu glucose, CK creatine kinase, CK-MB creatine kinase isoenzyme MB, SF serum ferritin, Myo myoglobin, HR hazard ratio, CI confidence interval