Table 1.

Case description and assays performed.

Case information	Assays performed		FCV results
Case no	Sex	Age (years)	Breed	Body weight (kg)	Phenotype	RNA-seq	FCV IHC and ISH	RNA-seq reads mapping to FCV	FCV IHC	FCV ISH
1	FS	8	DLH	2.9	FCGS	NO	YES	NA	NEG	NEG
2	MN	8	DSH	4.3	FCGS	NO	YES	NA	NEG	NEG
3	MN	7	DSH	5.9	FCGS	NO	YES	NA	NEG	NEG
4	FS	7	DLH	3.5	FCGS	YES*	NO	NO	NA	NA
5	MN	8	DSH	5	FCGS	YES	YES	YES	NEG	NEG
6	FS	9	Maine Coon	4	FCGS	NO	YES	NA	NEG	NEG
7	MN	12	DSH	4.6	FCGS	NO	YES	NA	NEG	NEG
8	FS	9	DSH	3.5	FCGS	YES	YES	NO	NEG	NEG
9	MN	3	DSH	5.1	FCGS	YES*	NO	YES	NA	NA
10	MN	11	DLH	4.9	FCGS	YES	YES	YES	NEG	NEG
11	MN	2	DSH	5	FCGS	YES	NO	YES	NA	NA
12	FS	3	DSH	3.5	FCGS	YES	YES	NO	NEG	NEG
13	FS	8	DSH	3.4	FCGS	YES*	YES	NO	NEG	NEG
14	MN	2	DSH	5.1	FCGS	YES	YES	YES	NEG	NEG
15	FS	11	DSH	3.4	FCGS	YES	NO	NO	NA	NA
16	FS	2	DSH	4.1	FCGS	YES	NO	NO	NA	NA
17	FS	4	DSH	7.6	FCGS	YES	YES	YES	NEG	NEG
18	FS	8	DSH	3.8	FCGS	YES	YES	YES	NEG	NEG
19	MN	10	DSH	5	FCGS	YES	NO	YES	NA	NA
20	MN	3	DSH	5.3	FCGS	YES	NO	YES	NA	NA
21	FS	5	DSH	5.1	HOM	YES (2)	NO	NO	NA	NA
23	F	1	Siamese	3	HOM	YES (2)	NO	NO	NA	NA
24	M	1	DSH	2.8	HOM	YES (2)	NO	NO	NA	NA
22	M	1	Siamese	4.2	HOM/HGIN	YES (2)	NO	NO	NA	NA
25	M	1	DSH	UNK	HOM/HGIN	YES (2)	NO	NO	NA	NA
26	M	1	DSH	UNK	HGIN	YES	NO	NO	NA	NA
28	FS	11	DSH	4.6	PER	YES	NO	NO	NA	NA
29	FS	3	DSH	4.5	PER	YES	NO	YES	NA	NA
30	MN	3	DSH	7	PER	YES	NO	NO	NA	NA
31	MN	5	Siamese	4.6	PER	YES	NO	NO	NA	NA
32	MN	9	DSH	4.5	PER	YES	NO	NO	NA	NA
33	MN	13	DSH	5.3	PER	YES	NO	NO	NA	NA
27	UNK	UNK	UNK	UNK	FCV negative control	NO	YES	NA	NEG	NEG
34	UNK	UNK	UNK	UNK	FCV positive control	NO	YES	NA	POS	POS

FCV Feline Calicivirus, IHC immunohistochemistry, ISH in situ hybridization, FS female spayed, MN male neutered, F female, M male, UNK unknown, DSH domestic shorthair, DLH domestic longhair, FCGS feline chronic gingivostomatitis, HOM healthy oral mucosa, HGIN healthy gingiva, PER periodontitis, NA not applicable, NEG negative, POS positive.

*Excluded from gene expression analysis.