Fig. 4. Summary of the biological functions of the genes assigned to associated variants identified from a survey of the literature.

Each panel contains a list of genes assigned by VEP or by eQTL/pQTL colocalisation to genetic associations with traits corresponding to the given cell-type, for which a literature search identified evidence of known function. Each list is stratified into functional categories relevant to the cell-type. Supplementary Data 4 contains a complete list of the associated variants, their VEP annotated genes, and relevant references to literature. The coloured symbolic annotations indicate genes assigned to variants which colocalise with eQTL (blue square), pQTL (orange circle), or disease GWAS associations (purple triangle). The gene(s) assigned by eQTL or pQTL colocalisation occasionally differ from the gene(s) assigned by VEP. We thank Joanna Westmoreland for the artwork.