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. 2023 Aug 18;8:315. doi: 10.1038/s41392-023-01559-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Summary of types of cancer caused by dysregulation of HH signaling pathway. The inner circle present five aspects of tumor biological behavior which are influenced by HH signaling pathway. The outer circle shows the representative cancers discussed in the review. The online resources in the picture were obtained from the website: www.699pic.com and www.vecteezy.com