Table 2.
Characteristics of participants with hospital-acquired venous thromboembolism within the Children’s Hospital-Acquired Thrombosis Registry.
| Covariate | VTE history N = 40 |
No VTE history N = 1216 |
P valuea |
|---|---|---|---|
| Age at admission (y), median (range; IQR) | 9 (0.1-20; 2-16) | 2 (0-20; 0.1-12) | <.001 |
| Age stratum (y) | .002 | ||
| Infant (birth to <1) | 7 (17.5) | 538 (44.2) | |
| Child (≥1 to <13) | 17 (42.5) | 393 (32.3) | |
| Teenager (≥13 to <21) | 16 (40) | 285 (23.4) | |
| Sex | .43 | ||
| Male | 20 (50) | 684 (56.3) | |
| Female | 20 (50) | 532 (43.8) | |
| Race | .71 | ||
| White | 20 (50) | 502 (41.3) | |
| Asian | 2 (5) | 71 (5.8) | |
| Black or African American | 4 (10) | 89 (7.3) | |
| American Indian or Native Alaskan | 0 (0) | 4 (0.3) | |
| Unknown | 11 (27.5) | 453 (37.3) | |
| Other | 3 (7.5) | 97 (8.0) | |
| Ethnicity | .23 | ||
| Hispanic/Latino | 16 (40) | 394 (32.4) | |
| Non-Hispanic | 22 (55) | 655 (53.9) | |
| Unknown | 2 (5) | 167 (13.7) | |
| Diagnosesb | |||
| Autoimmune/inflammatory | 1 (2.5) | 16 (1.3) | .43 |
| Cancer | 6 (15) | 139 (11.4) | .49 |
| Congenital heart disease | 16 (40) | 251 (20.6) | .003 |
| Other | 24 (60) | 599 (49.3) | .18 |
| Unknown/none | 0 (0) | 370 (30.4) | |
| VTE prophylaxis | .002 .88 |
||
| No | 20 (50) | 933 (78.0) | |
| Yes | 20 (50) | 263 (22.0) | |
| Mechanical only | 7 (35) | 95 (36.1) | |
| Pharmacologic only | 10 (50) | 133 (50.6) | |
| Both | 3 (15) | 35 (13.3) | |
| Days after admission to HA-VTE (d) | N = 40 | N = 1206 | .09 |
| Mean (SD) | 14 (22.2) | 20 (39.6) | |
| Median (range; IQR) | 7 (1-129; 3-16) | 9 (0-495; 4-20) | |
| Hospital location at VTE diagnosis | .45 | ||
| Non-ICU | 14 (35) | 498 (41.0) | |
| ICU | 26 (65) | 716 (60.0) | |
| Line related | .36 | ||
| No | 16 (40) | 379 (31.3) | |
| Yes | 23 (57.5) | 808 (66.7) | |
| Unknown | 1 (2.5) | 25 (2.1) | |
| VTE locationb | |||
| DVT upper extremity | 25 (62.5) | 556 (45.8) | .04 |
| DVT lower extremity | 11 (27.5) | 512 (42.1) | .07 |
| Cardiac | 2 (5) | 43 (3.5) | .65 |
| PE | 1 (2.5) | 31 (2.6) | 1.00 |
| ASVT | 1 (2.5) | 27 (2.2) | .60 |
| CSVT | 0 (0) | 68 (5.6) | .16 |
ASVT, abdominal site venous thrombosis; Cardiac, R atrium + cardiac ventricle; CSVT, cerebral sinus venous thrombosis; DVT, deep vein thrombosis; HA-VTE, hospital-acquired venous thromboembolism; ICU, intensive care unit; PE, pulmonary embolism; VTE, venous thromboembolism.
The parametric P value was calculated using analysis of variance for numerical covariates and the chi-square test for categorical covariates. The nonparametric P value was calculated using the Kruskal–Wallis test for numerical covariates and Fisher exact test for categorical covariates.
Each line represents a yes/no response, with only “yes” selections summarized as n (%) and P value.