Table 3.
Predictors of overall and late mortality in the whole cohort and in patients without active cancer.
| Characteristic | Overall mortality during follow-up (n = 361) |
Late mortality after >30 d (n = 283) |
Late mortality after >30 d in patients without active cancer (n = 180) |
|||
|---|---|---|---|---|---|---|
| Univariable model HR (95% CI) | Multivariable model HR (95% CI)a | Univariable model HR (95% CI) | Multivariable model HR (95% CI)a | Univariable model HR (95% CI) | Multivariable model HR (95% CI)a | |
| Age per decade | 1.50 (1.38-1.63) | 1.45 (1.30-1.61) | 1.56 (1.42-1.72) | 1.49 (1.32-1.68) | 2.17 (1.87-2.53) | 1.97 (1.66-2.33) |
| Sex (female) | 0.93 (0.75-1.16) | - | 0.91 (0.72-1.16) | - | 0.88 (0.65-1.19) | - |
| Obesity (BMI >30 kg/m2) | 0.77 (0.60-0.98) | 0.75 (0.57-0.98) | 0.69 (0.53-0.91) | 0.65 (0.48-0.87) | 0.68 (0.48-0.96) | 0.66 (0.45-0.98) |
| Comorbidities | ||||||
|---|---|---|---|---|---|---|
| Chronic heart failure | 2.13 (1.66-2.74) | 1.45 (1.09-1.92) | 2.30 (1.75-3.04) | 1.67 (1.23-2.28) | 3.57 (2.60-4.90) | 1.84 (1.31-2.59) |
| Coronary artery disease | 1.74 (1.35-2.23) | 1.14 (0.86-1.50) | 1.83 (1.39-2.42) | 1.12 (0.82-1.52) | 2.54 (1.83-3.52) | 1.04 (0.73-1.48) |
| Prior stroke | 1.95 (1.44-2.64) | 1.45 (1.05-1.99) | 1.85 (1.31-2.62) | 1.34 (0.93-1.92) | 2.38 (1.60-3.53) | 1.23 (0.82-1.86) |
| Arterial hypertension | 1.48 (1.17-1.87) | 0.83 (0.64-1.08) | 1.54 (1.19-1.99) | 0.93 (0.70-1.24) | 2.25 (1.59-3.19) | 0.90 (0.61-1.32) |
| Chronic pulmonary disease | 1.66 (1.28-2.17) | 2.03 (1.54-2.68) | 1.70 (1.26-2.28) | 2.16 (1.58-2.93) | 1.97 (1.39-2.81) | 2.22 (1.51-3.27) |
| Active cancer | 3.61 (2.88-4.53) | 3.76 (2.95-4.80) | 4.07 (3.17-5.23) | 4.22 (3.23-5.51) | - | - |
| Diabetes mellitus | 1.51 (1.16-1.96) | 1.33 (1.01-1.75) | 1.41 (1.05-1.90) | 1.27 (0.93-1.73) | 1.66 (1.17-2.37) | 1.20 (0.83-1.73) |
| Renal insufficiency | 1.99 (1.59-2.48) | 1.17 (0.91-1.52) | 1.97 (1.54-2.52) | 1.07 (0.80-1.41) | 3.35 (2.47-4.54) | 1.17 (0.82-1.65) |
| Anemia | 2.30 (1.85-2.85) | 1.80 (1.43-2.25) | 2.27 (1.79-2.89) | 1.84 (1.44-2.36) | 1.84 (1.36-2.50) | 1.62 (1.19-2.21) |
| Prior VTE | 0.76 (0.59-0.98) | 0.71 (0.55-0.92) | 0.84 (0.64-1.11) | - | 1.00 (0.72-1.39) | - |
Bold text indicates statistically significant results.
BMI, body mass index; HR, hazard ratio; VTE, venous thromboembolism.
a
Including all univariable predictors.