Table 2.
RRs and HRs with 95% CIs of VTE recurrence for hand grip strength ≤25th percentile compared to hand grip strength >25th percentile.
VTE recurrence by percentile groups | Person-years | Events | Crude RRa (95% CI) | Model 1 HR (95% CI) | Model 2 HR (95% CI) | Model 3 HR (95% CI) | Model 3 SHRb (95% CI) |
---|---|---|---|---|---|---|---|
Overall recurrence | |||||||
>25th percentile | 2012 | 55 | 2.73 (2.10-3.56) | 1 | 1 | 1 | 1 |
≤25th percentile | 723 | 35 | 4.84 (3.48-6.74) | 1.80 (1.12-2.91) | 1.99 (1.22-3.24) | 2.02 (1.23-3.30) | 1.86 (1.16-3.00) |
Recurrence after provoked | |||||||
>25th percentile | 1031 | 28 | 2.71 (1.87-3.93) | 1 | 1 | 1 | 1 |
≤25th percentile | 297 | 16 | 5.38 (3.30-8.79) | 2.31 (1.14-4.66) | 2.60 (1.22-5.51) | 2.59 (1.21-5.52) | 2.19 (1.07-4.45) |
Recurrence after unprovoked | |||||||
>25th percentile | 980 | 27 | 2.75 (1.89-4.02) | 1 | 1 | 1 | 1 |
≤25th percentile | 426 | 19 | 4.46 (2.85-7.00) | 1.42 (0.73-2.78) | 1.56 (0.79-3.08) | 1.54 (0.77-3.06) | 1.56 (0.79-3.08) |
Recurrence after PE | |||||||
>25th percentile | 850 | 24 | 2.82 (1.89-4.21) | 1 | 1 | 1 | 1 |
≤25th percentile | 314 | 11 | 3.50 (1.94-6.32) | 1.47 (0.67-3.21) | 1.65 (0.74-3.68) | 1.60 (0.72-3.57) | 1.27 (0.57-2.82) |
Recurrence after DVT | |||||||
>25th percentile | 1161 | 31 | 2.67 (1.88-3.80) | 1 | 1 | 1 | 1 |
≤25th percentile | 408 | 24 | 5.88 (3.94-8.77) | 1.97 (1.07-3.65) | 2.20 (1.17-4.13) | 2.22 (1.18-4.17) | 2.24 (1.19-4.21) |
Model 1: adjusted for age (at incident VTE) and sex.
Model 2: adjusted for age, sex, BMI, and height.
Model 3: adjusted for age, sex, BMI, height, cardiovascular disease (at cohort baseline), and active cancer (at time of VTE diagnosis).
BMI, body mass index; DVT, deep vein thrombosis; HR, hazard ratio; PE, pulmonary embolism; RR, recurrence rate; SHR, subdistribution HR; VTE, venous thromboembolism.
Recurrence rate per 100 person-years.
Denotes the HR after considering a competing risk by death.