Fig. 3.

The first dimension of shared associations between functional connectivity and clinical symptoms resembled a general psychopathology factor. A. The highest loading symptoms of this dimension. Loadings reflect correlations between LV weights and original data. B. Strength of edges and nodes that contributed to this dimension. Edges are coloured red for higher connectivity and blue for lower connectivity. Nodes are coloured based on network membership. C. Both increased and reduced connectivity in specific edges contributed. Magnitude in this plot reflects summarised edge strength across each network. D-E. Connectivity and symptom weights across diagnostic categories (left) and number of comorbidities (right). In these plots, the data is centred around the mean of no diagnosis. LV; latent variable. ADHD; attention-deficit hyperactivity disorder. ASD; autism spectrum disorder. ND; neurodevelopmental. Vis; visual network. SM; somatomotor network. Sal/VA; salience network. Cont; control network. DMN; default mode network. DA; dorsal attention network.