Table 1.
Systemic diseases of the investigated cohort
| Systemic disease | Preceding years n = 663 (%) |
Covid-19 year n = 298 (%) |
p-value |
|---|---|---|---|
| Allergy | 164 (24.7) | 83 (27.9) | |
| Lung disease total | 65 (9.8) | 32 (10.7) | |
| Asthma | 40 (6.0) | 19 (6.4) | |
| COPD | 16 (2.4) | 7 (2.3) | |
| Chronic bronchitis | 3 (0.5) | 3 (1.0) | |
| Tuberculosis | 1 (0.15) | 0 (0) | |
| Pneumonia | 1 (0.15) | 0 (0) | |
| COVID-19 | 0 (0) | 2 (0.7) | |
| Others | 4 (0.6) | 1 (0.3) | |
| Non-medication-related bleeding disorders total | 7 (1.1) | 5 (1.7) | |
| Hemorrhagic diathesis Thrombophilia | 4 (0.6) | 2 (0.7) | |
| 3 (0.5) | 3 (1.0) | ||
| Diabetes mellitus total | 52 (7.8) | 31 (10.4) | |
| Diabetes mellitus type I | 5 (0.8) | 2 (0.7) | |
| Diabetes mellitus type II | 47 (7.1) | 29 (9.7) | |
| Cardiac disease total | 86 (13.0) | 46 (15.4) | |
| Coronary heart disease | 54 (8.1) | 16 (5.4) | |
| Myocardial Infarction | 15 (2.3) | 5 (1.7) | |
| Arrhythmia | 36 (5.4) | 24 (8.1) | |
| Pacemaker | 9 (1.4) | 3 (1.9) | |
| Cardiac insufficiency | 24 (3.6) | 15 (5.0) | |
| Conatal heart disease | 0 (0) | 2 (0.7) | |
| Valve replacement | 6 (0.9) | 5 (1.7) | |
| Hypertension | 179 (27.0) | 73 (24.5) | |
| Vascular Disease | 42 (6.3) | 30 (10.1) | 0.042* |
| Liver/ bile disease | 32 (4.8) | 14 (4.7) | |
| Gastro-intestinal disease | 60 (9.0) | 25 (8.4) | |
| Kidney disease total | 26 (3.9) | 12 (4.0) | |
| Dialysis | 4 (0.6) | 1 (0.3) | |
| Thyroid disease | 98 (14.8) | 33 (11.1) | |
| Epilepsy | 19 (2.9) | 2 (0.7) | 0.032* |
| Glaucoma | 7 (1.1) | 4 (1.3) | |
| Rheumatic disease | 13 (2.0) | 9 (3.0) | |
| Psychiatric disease | 87 (13.1) | 33 (11.1) | |
| Neoplasia total | 64 (1.0) | 31 (10.4) | |
| Benign | 4 (0.6) | 2 (0.7) | |
| Semimalignant | 2 (0.3) | 2 (0.7) | |
| Malignant after performed therapy | 53 (8.0) | 25 (8.4) | |
| Malignant | 5 (0.8) | 2 (0.7) | |
| Solid malignant head and neck tumor | 16 (2.4) | 6 (2.0) | |
| Solid malignant tumor elsewhere | 33 (5.0) | 21 (7.0) | |
| Haemato-oncological disease | 9 (1.4) | 5 (1.7) |
Preceding years = control group: 2018–2020
Covid-19 year = test group: 2020–2021
*Fisher’s Exact Test