Table 3.
The Outcomes of Non-Frequent Exacerbation Patients with COPD After Propensity Score Matching
| Variables | Total (N=624) | Non-Frequent Exacerbation (N=312) | Frequent Exacerbation (N=312) | P value |
|---|---|---|---|---|
| ΔCAT, (Median, IQR) | 3 (−1, 8) | 4 (0, 9) | 2 (−1, 7) | 0.027 |
| MCID of CAT, n (%) | 0.032 | |||
| Yes | 368 (60.3) | 200 (64.5) | 168 (56.0) | |
| No | 242 (39.7) | 110 (35.5) | 132 (44.0) | |
| CSD of CAT, n (%) | 0.544 | |||
| Yes | 126 (20.7) | 61 (19.7) | 65 (21.7) | |
| No | 484 (79.3) | 249 (80.3) | 235 (78.3) | |
| Exacerbations during one year, (Median, IQR) | 0 (0, 1) | 0 (0, 1) | 0 (0, 1) | 0.004 |
| Exacerbations, n (%) | 0.027 | |||
| No | 426 (70.1) | 229 (74.1) | 197 (65.9) | |
| Yes | 182 (29.9) | 80 (25.9) | 102 (34.1) | |
| Frequent exacerbations, n (%) | <0.001 | |||
| No | 521 (86.2) | 285 (92.2) | 239 (79.9) | |
| Yes | 84 (13.8) | 24 (7.8) | 60 (20.1) | |
| Hospitalizations during one year, (Median, IQR) | 0 (0, 0) | 0 (0, 0) | 0 (0, 0) | 0.867 |
| Hospitalizations, n (%) | 0.960 | |||
| No | 521 (85.7) | 265 (85.8) | 256 (85.6) | |
| Yes | 87 (14.3) | 44 (14.2) | 43 (14.4) | |
| Mortality, n (%) | 16 (2.6) | 3 (1.0) | 13 (4.2) | 0.011 |
| Prescription outcomes, n (%) | 0.163 | |||
| Adjusted treatment | 126 (20.2) | 56 (17.9) | 70 (22.4) | |
| Continuous using | 498 (79.8) | 256 (82.1) | 242 (77.6) |
Note: The bold P values indicate statistical significance.
Abbreviations: COPD, Chronic Obstructive Pulmonary Disease; CAT, COPD Assessment Test; CSD, Clinically Symptom Deterioration; MCID, Minimal Clinically Important Difference; ΔCAT, CAT scores at 6-month visits from baseline.