Table 3.
The List of MALAT1 Targets Related to Biological Processes
GO ID | GO name | Fold Enrichment | p-val | Adjusted p-val | Number of Genes | Genes |
---|---|---|---|---|---|---|
GO:0015988 | Energy coupled proton transmembrane transport, against electrochemical gradient | 27,97 | 0.00057 | 0.04470 | 3 | MT-ND5, MT-CO1, MT-ND4 |
GO:0015990 | Electron transport coupled proton transport | 27,97 | 0.00057 | 0.04492 | 3 | MT-ND5, MT-CO1, MT-ND4 |
GO:0002486 | Antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent | 18,65 | 0.00019 | 0.01924 | 4 | HLA-C, HLA-E, HLA-A, HLA-B |
GO:0002484 | Antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway | 16,58 | 0.00027 | 0.02558 | 4 | HLA-C, HLA-E, HLA-A, HLA-B |
GO:0002483 | Antigen processing and presentation of endogenous peptide antigen | 11,78 | 0.00004 | 0.00496 | 6 | B2M, HLA-DRA, HLA-C, HLA-E, HLA-A, HLA-B |
GO:0019885 | Antigen processing and presentation of endogenous peptide antigen via MHC class I | 10,97 | 0.00022 | 0.02115 | 5 | B2M, HLA-C, HLA-E, HLA-A, HLA-B |
GO:0033119 | Negative regulation of RNA splicing | 10,29 | 0.00000 | 0.00090 | 8 | PTBP1, PCBP4, RPS13, SRSF9, SRSF6 |
GO:0002181 | Cytoplasmic translation | 8,72 | 0.00000 | 0.00000 | 29 | EIF3L, RPS16, RPL18A, RPL28, RPS13, RPL24… |
GO:0019883 | Antigen processing and presentation of endogenous antigen | 8,61 | 0.00016 | 0.01638 | 6 | B2M, HLA-DRA, HLA-C, HLA-E, HLA-A, HLA-B |
GO:0032069 | Regulation of nuclease activity | 8,48 | 0.00060 | 0.04572 | 5 | OAS3, OAS2, TMBIM6, RPS3, PRKCD |