Table 3.
Performance of PSR, PSVR, SZ, and Their Combination in the Prediction of the Severe, Moderate/Severe and Present EV
| Variables | Best Cutoff Value | AUROC (95% CI) | P | Se (%) | Sp (%) | |
|---|---|---|---|---|---|---|
| Predict the severe EV | PSR (1) | ≤1.510 | 0.648 (0.535–0.750) | 0.023 | 93.88 | 36.36 |
| PSVR (2) | ≤0.576 | 0.698 (0.587–0.795)* | 0.001 | 97.96 | 36.36 | |
| SZ (3) | >3564 | 0.695 (0.584–0.792)*,§ | 0.001 | 44.90 | 84.85 | |
| PSR+PSVR (4) | >0.744 | 0.735 (0.626–0.826)*,§ | <0.001 | 42.86 | 96.97 | |
| PSR+SZ (5) | >0.525 | 0.703 (0.591–0.798)*,§ | <0.001 | 85.71 | 51.52 | |
| PSR+PSVR+SZ (6) | >0.713 | 0.718 (0.608–0.812)*,§ | <0.001 | 51.02 | 84.85 | |
| PSVR+SZ (7) | >0.600 | 0.712 (0.602–0.807)*,§ | <0.001 | 71.43 | 63.64 | |
| Predict the moderate/severe EV | PSR (1) | ≤0.730 | 0.726 (0.617–0.819) | 0.001 | 56.06 | 87.5 |
| PSVR (2) | ≤0.168 | 0.759 (0.651–0.846) | <0.001 | 48.48 | 93.75 | |
| SZ (3) | >3564 | 0.711 (0.600–0.806)†,♯ | 0.003 | 39.39 | 93.75 | |
| PSR+PSVR (4) | >0.869 | 0.765 (0.659–0.852)†,♯ | <0.001 | 56.06 | 93.75 | |
| PSR+SZ (5) | >0.843 | 0.723 (0.613–0.816)†,♯ | 0.001 | 54.55 | 81.25 | |
| PSR+PSVR+SZ (6) | >0.848 | 0.757 (0.649–0.845)†,♯ | <0.001 | 62.12 | 87.50 | |
| PSVR+SZ (7) | >0.807 | 0.746 (0.638–0.836)†,♯ | <0.001 | 69.70 | 75 | |
| Predict the present EV | PSR (1) | ≤0.730 | 0.668 (0.556–0.768) | 0.007 | 53.42 | 100 |
| PSVR (2) | ≤0.172 | 0.685 (0.573–0.783) | 0.005 | 46.58 | 100 | |
| SZ (3) | >3313.5 | 0.631 (0.517–0.735) | 0.144 | 41.10 | 88.89 | |
| PSR+PSVR (4) | >0.896 | 0.696 (0.584–0.792)& | 0.002 | 52.05 | 100 | |
| PSR+SZ (5) | >0.898 | 0.642 (0.529–0.745) | 0.119 | 47.95 | 88.89 | |
| PSVR+PSR+SZ (6) | >0.904 | 0.639 (0.526–0.742) | 0.132 | 43.84 | 88.89 | |
| PSVR+SZ (7) | >0.870 | 0.647 (0.534–0.749) | 0.131 | 65.75 | 66.67 |
Notes: *(2), (3), (4), (5), (6), (7) VS (1) (P<0.05); §(3), (4), (5), (6), (7) VS (2) (P<0.05); †(3), (4), (5), (6), (7) VS (1) (P<0.05); ♯(3), (4), (5), (6), (7) VS (2) (P<0.05); &(4) VS (1), (2) (P<0.05).
Abbreviations: EV, esophageal varices; PSR, platelet count-to-spleen diameter ratio; PSVR, platelet count-to-spleen volume ratio; SZ, spleen size; AUROC, area under receiver operating characteristic curves; CI, confidence interval; Se, sensitivity; Sp, specificity; VS, versus.