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. 2023 Aug 19;22:160. doi: 10.1186/s12934-023-02175-2

Table 2.

BOT-A2 promoter table with DE number

Promoter name Gene annotation Simplified strain names Glucose Xylose
Countsnorm t1 Countsnorm t2 Log2 FC t2 vs t1 p-value t2 vs t1 Countsnorm t1 Countsnorm t2 Log2 FC t2 vs t1 p-value t2 vs t1
3877 Nitrate transporter UP1a–UP1e 5.8 ± 0.6 1963.6 ± 161.6 8.4 0 3.5 ± 0.4 619.3 ± 9.9 7.7 0
4847 Alcohol oxidase Fao1p UP2a–UP2e 32.4 ± 3.0 608.1 ± 91.7 4.2 9.5e-83 14.9 ± 3.5 281.5 ± 44.1 4.5 1.6e-89
0480 Carboxypeptidase Y inhibitor Tfs1p UP3a–UP3e 8.0 ± 2.6 310.4 ± 14.4 5.3 2.5e-75 80.1 ± 12.8 444.4 ± 22.3 2.7 4.1e-22
2184 Protein yippee-like Moh1p UP4a–UP4e 36.9 ± 2.8 547.3 ± 112.0 3.9 5.3e-49 70.4 ± 13.1 830.9 ± 143.4 3.8 5.0e-47
6908 Autophagy-related protein UP5a–UP5e 281.2 ± 95.5 2580.8 ± 215.5 3.2 5.4e-25 780.5 ± 159.9 4270.3 ± 697.5 2.7 3.5e-18
2391 Alcohol dehydrogenase UP6a–UP6e 14.9 ± 2.7 282.8 ± 27.7 4.2 1.1e-55 23.2 ± 5.6 386.8 ± 47.8 4.3 2.5e-57
6709 Fatty acid elongation protein UP7a–UP7e 182.2 ± 78.5 1227.2 ± 83.6 2.7 4.6e-19 89.4 ± 18.1 1371.3 ± 24.1 4.2 1.4e-42
0568 Protein Orm1p UP8a–UP8e 42.8 ± 9.6 282.1 ± 11.6 2.7 8.8e-23 65.9 ± 16.8 335.7 ± 14.3 2.6 9.8e-21
5111 Dehydrogenase/reductase UP9a-UP9e 75.9 ± 11.3 463.6 ± 35.7 2.6 4.7e-24 14.9 ± 2.9 442.8 ± 90.8 5.1 8.7e-88
0530 Ribosome-associated molecular chaperone Ssb2p DN1a–DN1e 297.1 ± 29.8 6.0 ± 0.8 -5.6 1.6e-57 185.9 ± 80.3 3.6 ± 1.4 -5.4 3.0e-51
3356 Diphosphomevalonate decarboxylase Mvd1p DN2a–DN2e 25.1 ± 1.9 0.7 ± 0.2 -5.2 9.9e-50 21.2 ± 4.9 0.4 ± 0.3 -5.4 1.3e-38
5449 Epsin-3 Ent3p DN3a–DN3e 9.5 ± 0.6 0.6 ± 0.1 -4.1 2.8e-13 7.4 ± 2.8 0.8 ± 0.7 -3.0 8.6e-8
4071 APC/C activator protein Cdc20p DN4a–DN4e 19.3 ± 5.0 1.6 ± 0.3 -3.6 4.1e-19 17.3 ± 8.3 2.2 ± 0.3 -2.7 1.6e-11
5360 2-oxoglutarate dehydrogenase (mitoch.) Kgd1p DN5a–DN5e 102.5 ± 18.3 9.4 ± 0.7 -3.5 1.8e-42 39.4 ± 5.0 6.0 ± 1.7 -2.5 1.3e-21
5958 Mitochondrial inner membrane protein Oxa1p DN6a–DN6e 67.0 ± 7.5 3.9 ± 0.8 -4.1 5.5e-48 33.9 ± 6.7 1.3 ± 0.5 -4.4 5.94e-50

Promoters are named after four last digits of the locus tags of the genes they precede. Countsnorm are the average normalized counts from three biological replicates, normalized using the geTMM method [117]. The promoter from MEP2 (RHTO_01680) in strain NP11 was also evaluated (strains UP10a-UP10e)