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. Author manuscript; available in PMC: 2024 Aug 1.
Published in final edited form as: Alzheimers Dement. 2023 Feb 23;19(8):3519–3527. doi: 10.1002/alz.12974

Figure 1. MarkVCID Endothelial Signaling Kit Study Design.

Figure 1.

Consortium sites with enrolled subjects for endothelial signaling biomarker kit development. Random resampling resulted in three independent cohorts with a holdout cohort for validation. After measurement of plasma PlGF (pg/mL), intent to analyze cohorts were reduced if sample CoV>15%. Independent analytic cohorts were used to determine primary and secondary cognitive and imaging study outcomes. UTSCSA = University of Texas Health Science Center at San Antonio; UKY = University of Kentucky; UCSF = University of California San Francisco; UNM = University of New Mexico; JHU = Johns Hopkins University. * Analytic site information available in eTable 2. Parentheses = subject number.