Table 1.
Characteristics of the study population by history of endometriosis
| N (%) or Mean (SD) | Black Participants | White Participants | ||
|---|---|---|---|---|
| N = 2724 | N = 5281 | |||
| Endometriosis = No | Endometriosis = Yes | Endometriosis = No | Endometriosis = Yes | |
| (N = 2551) | (N = 173) | (N = 4910) | (N = 371) | |
| Site | ||||
| AACES | 1232 (48.3) | 94 (54.3) | N/A | N/A |
| BWHS | 644 (25.3) | 54 (31.2) | N/A | N/A |
| CCCCS | 116 (4.6) | 7 (4.1) | 617 (12.6) | 36 (9.7) |
| LACOCS | 260 (10.2) | 11 (6.4) | 2790 (56.8) | 170 (45.8) |
| NCOCS | 299 (11.7) | 7 (4.1) | 1503 (30.6) | 165 (44.5) |
| Case-Control Status | ||||
| Cases | 870 (34.1) | 81 (46.8) | 1998 (40.7) | 198 (53.4) |
| Controls | 1681 (65.9) | 92 (53.2) | 2912 (59.3) | 173 (46.6) |
| Age at Ovarian Cancer Diagnosis or Interview | 55.05±11.46 | 53.48±9.23 | 56.83±11.52 | 54.99±10.16 |
| Histotype * | ||||
| High-Grade Serous | 571 (65.6) | 38 (46.9) | 1218 (61.0) | 97 (49.0) |
| Low-Grade Serous | 31 (3.6) | 1 (1.2) | 76 (3.8) | 5 (2.5) |
| Endometrioid | 62 (7.1) | 22 (27.2) | 159 (8.0) | 27 (13.6) |
| Clear Cell | 29 (3.3) | 6 (7.4) | 144 (7.2) | 33 (16.7) |
| Mucinous | 50 (5.8) | 2 (2.5) | 133 (6.7) | 11 (5.6) |
| Carcinosarcoma | 21 (2.4) | 3 (3.7) | 40 (2.0) | 2 (1.0) |
| Other epithelial | 93 (10.7) | 5 (6.2) | 228 (11.4) | 23 (11.6) |
| Synchronous | 13 (1.5) | 4 (4.9) | 0 (0.0) | 0 (0.0) |
| Stage * | ||||
| Localized | 163 (18.7) | 28 (34.6) | 388 (19.4) | 61 (30.8) |
| Regional | 75 (8.6) | 9 (11.1) | 193 (9.7) | 28 (14.1) |
| Distant | 577 (66.3) | 41 (50.6) | 1398 (70.0) | 104 (52.5) |
| Missing | 55 (6.3) | 3 (3.7) | 19 (1.0) | 5 (2.5) |
| Education | ||||
| HS or less | 945 (37.0) | 44 (25.4) | 934 (19.0) | 55 (14.8) |
| Some college | 664 (26.0) | 42 (24.3) | 1149 (23.4) | 97 (26.2) |
| College grad | 543 (21.3) | 45 (26.0) | 1312 (26.7) | 114 (30.7) |
| Grad/prof school | 395 (15.5) | 42 (24.3) | 1515 (30.9) | 105 (28.3) |
| Missing | 4 (0.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| Parity | ||||
| No pregnancies | 406 (15.9) | 50 (28.9) | 1044 (21.3) | 112 (30.2) |
| 1–2 pregnancies | 1131 (44.3) | 88 (50.9) | 2310 (47.1) | 182 (49.1) |
| ≥3 pregnancies | 1012 (39.7) | 34 (19.7) | 1556 (31.7) | 77 (20.8) |
| Missing | 2 (0.1) | 1 (0.6) | 0 (0.0) | 0 (0.0) |
| Oral Contraceptive Duration | ||||
| Never | 857 (33.6) | 42 (24.3) | 1833 (37.3) | 83 (22.4) |
| <5 years | 922 (36.1) | 54 (31.2) | 1647 (33.5) | 146 (39.4) |
| ≥5 years | 746 (29.2) | 75 (43.4) | 1373 (28.0) | 137 (36.9) |
| Missing | 26 (1.0) | 2 (1.2) | 57 (1.2) | 5 (1.4) |
| Body Mass Index, kg/m 2 | ||||
| <25 | 511 (20.0) | 39 (22.5) | 2631 (53.6) | 194 (52.3) |
| 25–29.9 | 763 (29.9) | 54 (31.2) | 1293 (26.3) | 96 (25.9) |
| 30–34.9 | 610 (23.9) | 45 (26.0) | 584 (11.9) | 46 (12.4) |
| ≥35 | 650 (25.5) | 35 (20.2) | 362 (7.4) | 34 (9.2) |
| Missing | 17 (0.7) | 0 (0.0) | 40 (0.8) | 1 (0.3) |
| Smoking Status | ||||
| Never smoker | 1398 (54.8) | 94 (54.3) | 2538 (51.7) | 189 (50.9) |
| Former smoker | 734 (28.8) | 46 (26.6) | 1708 (34.8) | 134 (36.1) |
| Current smoker | 417 (16.4) | 33 (19.1) | 642 (13.1) | 46 (12.4) |
| Missing | 2 (0.1) | 0 (0.0) | 22 (0.5) | 2 (0.5) |
| Tubal Ligation Ever | ||||
| No | 1567 (61.4) | 118 (68.2) | 4006 (81.6) | 304 (81.9) |
| Yes | 913 (35.8) | 51 (29.5) | 896 (18.3) | 67 (18.1) |
| Missing | 71 (2.8) | 4 (2.3) | 8 (0.2) | 0 (0.0) |
| First-Degree Family History of Breast or Ovarian Cancer | ||||
| No | 1952 (76.5) | 130 (75.1) | 3985 (81.2) | 294 (79.3) |
| Yes | 487 (19.1) | 35 (20.2) | 875 (17.8) | 69 (18.6) |
| Missing | 112 (4.4) | 8 (4.6) | 50 (1.0) | 8 (2.2) |
| Menopausal Status | ||||
| Premenopausal | 873 (34.2) | 62 (35.8) | 1547 (31.5) | 131 (35.3) |
| Postmenopausal | 1676 (65.7) | 111 (64.2) | 3355 (68.33) | 240 (64.7) |
| Missing | 2 (0.1) | 0 (0.0) | 8 (0.2) | 0 (0.0) |
| Hormone Therapy Use Duration | ||||
| Never | 2009 (78.8) | 123 (71.1) | 2879 (58.6) | 194 (52.3) |
| <5 years | 324 (12.7) | 27 (15.6) | 833 (17.0) | 68 (18.3) |
| ≥5 years | 206 (8.1) | 21 (12.1) | 1104 (22.5) | 97 (26.2) |
| Missing | 12 (0.5) | 2 (1.2) | 94 (1.9) | 12 (3.2) |
| Age at Menarche | ||||
| <11 years | 274 (10.7) | 20 (11.6) | 313 (6.4) | 33 (8.9) |
| 11–12 years | 1048 (41.1) | 81 (46.8) | 2002 (40.8) | 154 (41.5) |
| 13–14 years | 903 (35.4) | 52 (30.1) | 2049 (41.7) | 149 (40.2) |
| 15–16 years | 267 (10.5) | 14 (8.1) | 465 (9.5) | 28 (7.6) |
| ≥17 years | 53 (2.1) | 6 (3.5) | 73 (1.5) | 6 (1.6) |
| Missing | 6 (0.2) | 0 (0.0) | 8 (0.2) | 1 (0.3) |
| Premenopausal Hysterectomy | ||||
| No | 1961 (76.9) | 108 (62.4) | 4148 (84.5) | 246 (66.3) |
| Yes | 576 (22.6) | 65 (37.6) | 744 (15.2) | 123 (33.2) |
| Missing | 14 (0.6) | 0 (0.0) | 18 (0.4) | 2 (0.5) |
| History of Infertility † | ||||
| No | 1714 (74.8) | 99 (61.1) | 1674 (79.0) | 128 (63.7) |
| Yes | 573 (25.0) | 63 (38.9) | 443 (20.9) | 73 (36.3) |
| Missing | 4 (0.2) | 0 (0.0) | 3 (0.1) | 0 (0.0) |
*
Distributions of histotype and stage are only shown for cases
†
History of infertility was not collected for LACOCS: 260 Black women without endometriosis, 11 Black women with endometriosis, 2790 White women without endometriosis, 170 White women with endometriosis