Table 2.
All histotypes | High-Grade Serous | Low-Grade Serous | Endometrioid | Clear Cell | Mucinous | pheterogeneity | Low-Grade Serous, Endo, & Clear Cell | |
---|---|---|---|---|---|---|---|---|
OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | between histotypes | OR (95% CI) | |
All participants (cases/controls) | 3147/4858 | 1924/4858 | 113/4858 | 270/4858 | 212/4858 | 196/4858 | 595/4858 | |
Yes | 1.75 (1.45–2.11) | 1.40 (1.11–1.76) | 0.97 (0.41–2.30) | 3.30 (2.31–4.71) | 3.93 (2.64–5.83) | 1.31 (0.72–2.36) | <0.001 | 3.05 (2.31–4.02) |
Black participants (cases/controls) | 951/1773 | 609/1773 | 32/1773 | 84/1773 | 35/1773 | 52/1773 | 151/1773 | |
Yes | 2.12 (1.50–3.00) | 1.63 (1.06–2.51) | 1.00 (0.13–7.99) | 7.06 (3.86–12.91) | 4.82 (1.81–12.85) | 0.89 (0.21–3.82) | 0.047 | 4.91 (2.93–8.23) |
White participants (cases/controls) | 2196/3085 | 1315/3085 | 81/3085 | 186/3085 | 177/3085 | 144/3085 | 444/3085 | |
Yes | 1.58 (1.26–1.98) | 1.31 (1.00–1.72) | 0.98 (0.38–2.55) | 2.17 (1.36–3.45) | 3.48 (2.24–5.41) | 1.41 (0.73–2.70) | 0.004 | 2.39 (1.71–3.34) |
pheterogeneity by race | 0.22 | 0.56 | 0.94 | 0.003 | 0.64 | 0.50 |
Odd ratios were adjusted for site, age at diagnosis, education, parity, oral contraceptive use, BMI, smoking status, tubal ligation, family history of breast or ovarian cancer, menopausal status, post-menopausal hormone duration, age at menarche, and premenopausal hysterectomy.