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. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: Hepatology. 2023 Mar 22;78(3):803–819. doi: 10.1097/HEP.0000000000000354

Figure 1. TAA and CLP combination results in rapid and sustained loss of liver function.

Figure 1.

Mice (male and female) were treated with TAA (200mg/L in the drinking water) and subjected to cecal ligation and puncture (CLP) or sham surgery. A. Treatment groups. B. Liver/body weight ratios and weight loss after CLP surgery. C-E. INR, prothrombin time (PT) (C) in male mice and serum albumin (D) and prothrombin time (PT) in female mice (E) as indicated. F. Serum ALT (top), Bilirubin (middle) and blood urea (BUN, bottom) in sham and CLP mice as indicated. *, P<0.05, **, P<0.01.