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. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: Hepatology. 2023 Mar 22;78(3):803–819. doi: 10.1097/HEP.0000000000000354

Figure 4. TAA and CLP combination results in C/EBPβ activation.

Figure 4.

A-B. Mice (male and female) were treated with TAA and subjected to cecal ligation and puncture or sham surgery. Liver section from indicated groups of mice at 24 hours (A) and 48 hours (B) post-surgery were stained using C/EBPβ specific antibodies (total C/EBPβ). C-E Chromatin immunoprecipitation using C/EBPβ specific antibodies (total C/EBPβ) or HNF4α specific antibodies in four groups of mice. Data is presented as percent input. N= 4–8 mice per group. *, P<0.05. F. Relative gene expression changes in TAA, CLP and TAA/CLP mice of top genes bound by C/EBPβ at 3 hours after partial hepatectomy. Right. Relative gene expression in mouse primary hepatocytes isolated from Cebpb floxed mice treated with Ad-Cre vector or control for 48 hours. *, P<0.05, **, P<0.01.