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. Author manuscript; available in PMC: 2024 Sep 1.
Published in final edited form as: Hepatology. 2023 Mar 22;78(3):803–819. doi: 10.1097/HEP.0000000000000354

Figure 6. Hepatocyte specific Cebpb knockout protects from mortality and loss of liver function in TAA/CLP mice.

Figure 6.

Cebpb floxed mice received AAV-TBG.CRE (KO) or AAV.TBG.control (WT) at 10^11 gc/mouse 1 week before surgeries. A. C/EBPβ protein levels in hepatocyte specific knockout mice. Right. Relative gene expression at one day after CLP. B. Serum ALT and AST in wild type (WT) and knockout mice (KO). C. INR and PT in mice before AAV injection, one day before CLP and one day after CLP. *, P<0.05, **, P<0.01. D. Survival in TAA/CLP mice. N=17 per group. E-F. Whole liver mRNA in these mice *, P<0.05, **, P<0.01.