Table 3.
Odds ratio for risk factors of triple-negative breast cancers compared with non-triple negative controls.
| Variables | Categories | N (case/control) | ORa (95%CI) | p-value | ORb (95%CI) | p-value |
|---|---|---|---|---|---|---|
| Heightc (in cm) | < 150 | 93/224 | 1.00 | 1.00 | ||
| ≥ 150 | 153/391 | 0.88 (0.63–1.23) | 0.466 | 1.03 (0.71–1.49) | 0.875 | |
| Body mass index (in kg/m2) | ≤ 24.9 | 120/275 | 1.00 | 1.00 | ||
| > 24.9 | 134/376 | 0.89 (0.63–1.24) | 0.496 | 0.94 (0.65–1.34) | 0.750 | |
| Waist circumferenced (in cm) | ≤ 80 | 91/177 | 1.00 | 1.00 | ||
| > 80 | 157/434 | 0.64 (0.45–0.90) | 0.012 | 0.63 (0.40–1.00) | 0.053 | |
| Waist to hip ratiod | ≤ 0.85 | 119/255 | 1.00 | 1.00 | ||
| > 0.85 | 129/353 | 0.72 (0.51–1.00) | 0.056 | 0.76 (0.53–1.08) | 0.135 | |
| Age at menarche (in years) | ≤ 13 | 93/274 | 1.00 | 1.00 | ||
| > 13 | 156/357 | 1.33 (0.95–1.87) | 0.088 | 1.31 (0.91–1.88) | 0.144 | |
| Number of full-term pregnanciese | ≤ 3 | 184/494 | 1.00 | 1.00 | ||
| > 3 | 58/121 | 1.35 (0.89–2.05) | 0.149 | 1.20 (0.75–1.91) | 0.442 | |
| Breast feeding | Ever | 7/25 | 1.00 | 1.00 | ||
| Never | 231/586 | 1.16 (0.48–2.80) | 0.733 | 1.35 (0.51–3.61) | 0.540 | |
| Age at first full-term pregnancyf (in years) | ≤ 24 | 149/367 | 1.00 | 1.00 | ||
| > 24 | 88/244 | 0.95 (0.67–1.35) | 0.809 | 1.02 (0.68–1.53) | 0.894 | |
| Spontaneous abortion | No | 201/515 | ||||
| Yes | 42/104 | 1.11 (0.73–1.69) | 0.619 | 1.23 (0.79–1.92) | 0.346 | |
| Time between menarche and first full-term pregnancyf (in years) | < 10 | 146/361 | 1.00 | 1.00 | ||
| ≥ 10 | 88/240 | 0.99 (0.69–1.40) | 0.957 | 1.12 (0.75–1.67) | 0.557 | |
| Induced abortion | No | 179/439 | 1.00 | 1.00 | ||
| Yes | 21/66 | 0.82 (0.47–1.43) | 0.500 | 0.95 (0.53–1.69) | 0.863 | |
| Current residence | Rural | 74/174 | 1.00 | 1.00 | ||
| Urban | 160/439 | 0.84 (0.58–1.20) | 0.343 | 0.92 (0.62–1.37) | 0.710 | |
| Tobacco use | Never | 200/533 | 1.00 | 1.00 | ||
| Ever | 49/97 | 1.30 (0.85–2.00) | 0.219 | 1.10 (0.69–1.74) | 0.681 | |
| Oral contraceptives | Never | 215/555 | 1.00 | 1.00 | ||
| Ever | 20/58 | 0.89 (0.49–1.59) | 0.702 | 1.01 (0.54–1.89) | 0.961 | |
| Family history of breast/ovarian cancer | No | 241/619 | 1.00 | 1.00 | ||
| Yes | 10/23 | 1.19 (0.53–2.68) | 0.633 | 1.49 (0.63–3.50) | 0.352 | |
| Family history of any cancer | No | 214/534 | 1.00 | 1.00 | ||
| Yes | 35/107 | 0.81 (0.51–1.27) | 0.363 | 0.82 (0.50–1.34) | 0.436 | |
| Socio-economic status (Modified Kuppuswamy’s Socioeconomic Scale) | ≤ 5 | 68/152 | 1.00 | 1.00 | ||
| > 5 | 182/484 | 0.73 (0.50–1.06) | 0.106 | 0.76 (0.50–1.06) | 0.213 |
OR: odds ratio; CI: confidence interval.
aAdjusted for age and region of residence.
bAdjusted for age, region of residence, age at first full-term pregnancy, education, waist-to-hip ratio, height, menopausal status, current rural–urban status, and total number of induced and spontaneous abortions.
cAdjusted for weight instead of height.
dAdjusted for body mass index instead of height and waist-to-hip ratio.
eNot adjusted for age at first full-term pregnancy.
fAdjusted for number of pregnancies instead of age at first full-term pregnancy.