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. 2023 Jul 29;9(8):e18443. doi: 10.1016/j.heliyon.2023.e18443

Fig. 2.

Fig. 2

Concentration-time profiles of RD2 in (A) plasma and (B) CSF following daily oral administration of 3 mg/kg or 30 mg/kg of RD2 for three months. CSF-values of 3 mg/kg treated animals were below the lower limit of quantification (LLOQ) of 0.5 ng/mg and were therefore excluded from the graph. Data is presented as mean±SEM; n = 11 to 12.