Table 2.
Alignment of the Age-Related Metrics Between Macaques and Humans
| Age at Inflection Point (Y) | |||||
|---|---|---|---|---|---|
| Mean (SD) in Adult | Chronologic Age | Relative Age | |||
| H.S. | M.F.* | H.S. | M.F. | M.F.† | |
| AL | 23.49 mm (1.35)28 | ∼20–252,15 | |||
| All | 18.40 mm (1.03) | 14.96 | 44.88 | ||
| F | 18.04 mm (0.86) | 13.88 | 41.64 | ||
| M | 18.75 mm (1.05) | 15.47 | 46.41 | ||
| LT | 4.37 mm (0.43)28 | ∼102,15–17 | |||
| All | 3.19 mm (0.25) | 9.66 | 28.98 | ||
| F | 3.20 mm (0.25) | 9.40 | 28.2 | ||
| M | 3.18 mm (0.25) | 10.08 | 30.24 | ||
| ACD | 3.10 mm (0.47)28 | ∼1224,25,28 | |||
| All | 3.14 mm (0.22) | 12.23 | 36.69 | ||
| F | 3.06 mm (0.21) | 11.26 | 33.78 | ||
| M | 3.21 mm (0.21) | 12.93 | 38.79 | ||
| CCT | 544 µm (38)28 | ∼1126,27 | |||
| All | 445 µm (29) | 10.73 | 32.19 | ||
| F | 440 µm (26) | 9.81 | 29.43 | ||
| M | 449 µm (30) | 12.64 | 37.92 | ||
| CR | 7.69 mm (0.28)28 | ∼12,15 | NA‡ | NA‡ | |
| All | 5.77 mm (0.17) | ||||
| F | 5.72 mm (0.15) | ||||
| M | 5.82 mm (0.18) | ||||
| WTW | 11.80 mm (0.42)28 | ∼12,15 | NA‡ | NA‡ | |
| All | 9.64 mm (0.36) | ||||
| F | 9.49 mm (0.37) | ||||
| M | 9.74 mm (0.32) | ||||
M.F., macaca fascicularis; H.S., homo sapiens.
*
Included data from macaques >9 years old.
†Relative age in macaques was calculated by multiplying the chronologic age in macaques by the ratio of 3:1 (average lifespan ratio between humans and macaques).
‡No significant trend detected.