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. 2023 Aug 3;94(4):e2023174. doi: 10.23750/abm.v94i4.14289

Table 10.

Opioids commonly used in pediatric age - O: oral. IV: intravenous. SC: subcutaneous.

Drug Starting dose IV/SC Starting dose oral Notes
Codeine - 0.5-1 mg/kg every 3-4 hours Nausea, vomit
Hydromorphone Bolus: 0.015 mg/kg every 2-4 hours
Infusion: 0.006 mg/kg/h
0.06 mg/kg every 3-4 hours Nausea, vomit, urinary retention
Morphine Bolus: 0.05-0.1 mg/kg every 2-4 hours
Infusion: 0.03 mg/kg/h
0.5-1 mg/kg every 3-4 hours Nausea, vomit, urinary retention
Fentanyl Bolus: 0.5-1 γ/kg every 1-2 hours
Infusion: 0.5-3 γ /kg/h
- Nausea, vomit, urinary retention, itching, respiratory depression
Remifentanyl Bolus: 0.1-0.5 γ/kg every hour
Infusion: 0.1-0.25 γ /kg/min
- Nausea, vomit, urinary retention, itching, respiratory depression
Sufentanyl Bolus: 0.2 γ /kg every hour
Infusion: 0.1-0.5 γ /kg/min
- Respiratoty depressione, hemodynamic alterations