Skip to main content
. 2023 Aug 21;2023(8):CD015422. doi: 10.1002/14651858.CD015422.pub2

Comparison 1. Topical repellents versus placebo or no intervention.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1.1 Malaria incidence (case and infection) 4 61651 Rate Ratio (IV, Fixed, 95% CI) 0.74 [0.56, 0.98]
1.1.1 Case incidence 1 48838 Rate Ratio (IV, Fixed, 95% CI) 0.66 [0.32, 1.36]
1.1.2 Infection incidence 3 12813 Rate Ratio (IV, Fixed, 95% CI) 0.76 [0.56, 1.02]
1.2 Malaria incidence (use of other interventions) 4 61651 Rate Ratio (IV, Fixed, 95% CI) 0.74 [0.56, 0.98]
1.2.1 Use of bednets and other interventions 3 60754 Rate Ratio (IV, Fixed, 95% CI) 0.78 [0.51, 1.18]
1.2.2 Without use of bednets and other interventions 1 897 Rate Ratio (IV, Fixed, 95% CI) 0.71 [0.49, 1.04]
1.3 Malaria incidence (by risk population) 4 61651 Rate Ratio (IV, Fixed, 95% CI) 0.74 [0.56, 0.98]
1.3.1 High‐risk population 3 57643 Rate Ratio (IV, Fixed, 95% CI) 0.76 [0.58, 1.01]
1.3.2 Non‐high risk population 1 4008 Rate Ratio (IV, Fixed, 95% CI) 0.18 [0.02, 1.40]
1.4 Reported adverse events in the topical repellents arm of included studies 0   Other data No numeric data
1.5 Malaria prevalence 4 55366 Odds Ratio (IV, Fixed, 95% CI) 0.81 [0.67, 0.97]
1.5.1 No refugees 2 53321 Odds Ratio (IV, Fixed, 95% CI) 0.90 [0.73, 1.11]
1.5.2 Refugees 2 2045 Odds Ratio (IV, Fixed, 95% CI) 0.61 [0.44, 0.86]
1.6 Malaria prevalence (per‐protocol analysis) 2   Odds Ratio (IV, Fixed, 95% CI) 0.81 [0.42, 1.56]
1.7 Anaemia 1 587 Odds Ratio (M‐H, Fixed, 95% CI) 1.12 [0.81, 1.55]
1.8 All‐cause fever 1 4008 Rate Ratio (IV, Fixed, 95% CI) 0.42 [0.32, 0.56]
1.9 Adherence to the intervention 0   Other data No numeric data