Kroeger 1997.

Study characteristics
Methods	cRCT Unit of randomization: villages ICC: not reported Trial duration: 7 months (treatment period of 6 months)
Participants	Adults or children living in malaria‐endemic regions Non‐high risk population Endemic region for P vivax Participants not screened for hypnozoites
Interventions	Topical repellent: soap with 0.5% DEET and 20% permethrin Controls: no intervention Co‐interventions: none Treatment arms: Intervention: 9 communities (total population not reported) Control: 9 villages (total population not reported)
Outcomes	Incidence of recorded adverse events (including skin irritation, local pain, eye irritation, irritation of upper airways, nausea, vomiting, headaches, dizziness or confusion, allergic or anaphylactic reactions, and systemic toxicity) Adherence to regular usage of the intervention (defined based on recommendations provided by researchers to participants of individual trials) Human biting rate (HBR)
Notes	Malaria case incidence was listed as an outcome, but it was self‐reported, and raw data for this outcome is not presented Carried out in Ecuador and Peru Funded by: Commission of European Communities, Catholic Organization for Development